程国林
发布时间:2017-06-23 浏览次数:

Guolin Cheng (教授/博导)

Group

Website:    http://www.escience.cn/people/glcheng/index.html

Address:    B612, Fanhua Science Building, 668 Jimei Avenue, Xiamen 361021, P.R. China

E-mail:       glcheng@hqu.edu.cn  

Professional Experience

2017-Current - ProfessorCollege of Materials Science & Engineering, Huaqiao University

2015-2017Associate Professor, School of Biomedical Sciences, Huaqiao University

2011-2014Assistant Professor, School of Biomedical Sciences, Huaqiao University

Education

2014-2015Visiting Scholar   Biological and Medicinal Chemistry, The Scripps Research Institute, California, USA

2007-2011 - Ph.D.   Organic Chemistry, Tsinghua University, Beijing, China

2005-2007 - M.S.    Organic Chemistry, Zhejiang University, Hangzhou, China

2001-2005 - B.S.   Applied Chemistry, Northeast Petroleum University, Daqing, China

Research Interests

Transition metal-catalyzed reactions;

Heterocyclic compounds synthesis via cascade reactions;

Total synthesis of natural alkaloids.

Grants & Talent Plan

3). 2017-2020  National Natural Science Foundation of China (21672075), (PI)

2). 2013-2015  National Natural Science Foundation of China (21202048), (PI)

1). 2013-2015  Natural Science Foundation of Fujian Province, China (2013J01050), (PI)

1.  Program for New Century Excellent Talents in Fujian Province University(2017, NCETFJ); 2.  Talents in Xiamen (2017, 厦门市重点人才);3.  Outstanding Youth Scientific Research Cultivation Plan in Fujian Province University( 2015)

Members

2018年 计划招化学相关专业2-3名硕士研究生(接受调剂生),1-2名博士研究生。

2017级 文思、刘景

2016级 余佳、吕薇薇、葛百潞

2015级 美国访学一年

2014级 朱瑞丰(国家奖学金)、薛露露

2013级 翁云翔(清华大学读博

以下为与崔教授合作指导:

2012级 杨西发(大连化物所读博)、李鹏飞(睿智化学

2011级 曾小宝(国家奖学金,清华大学读博)、王雪松(清华大学读博

2010级 沈金海(国家奖学金

Publications 

37. Xue, L.; Cheng, G.*;  Zhu, R.; Cui, X. *, Acid-Promoted Oxidative Methylenation of 1,3-DicarbonylCompounds with DMSO: Application to the Three-Component Synthesis of Hantzsch-TypePyridines. RSC Adv., 2017, 7, 44009-44012 (IF3.108)


36. Cheng, G.*; Xue, L.; Weng, Y.; Cui, X. *, Transition-Metal-Free Cascade Approach toward 2‑Alkoxy/2-Sulfenylpyridines and Dihydrofuro[2,3‑b]pyridines by Trapping In Situ Generated 1,4-Oxazepine. J. Org. Chem. 2017, DOI: 10.1021/acs.joc.7b01541 (IF4.785)

35. Cheng, G.;+ Wang P.; + Yu, J.-Q.*, Meta-CH Arylation and Alkylation of Benzylsulfonamide Enabled by a Pd(II)/Isoquinoline Catalyst. Angew. Chem., Int. Ed. 2017, 56, 8183-8186. (IF 11.994)                                

34. Ding, Q.; Ye, S.; Cheng, G.; Wang, P.; Farmer, M. E.; Yu, J.-Q.*, Ligand-Enabled meta-Selective C–H Arylation of Nosyl-Protected Phenethylamines, Benzylamines, and 2-Aryl Anilines J. Am. Chem. Soc.2017, 139, 417-425. (IF13.858)

 

33.  Zhu, R.; Cheng, G.*; Jia, C.; Xue, L.; Cui, X.*, Access to C4-Functionalized Quinolines via Copper-Catalyzed Tandem Annulation of Alkynyl Imines with Diazo Compounds. J. Org. Chem. 2016, 81, 7539-7544. (IF4.785)

32.  Shen, J. H.; Yang, X. F.; Wang, F. Y.; Wang, Y.; Cheng, G.; Cui, X. L.*, Base-mediated regiospecific cascade synthesis of N-(2-pyridyl)pyrroles from N-propargylic beta-enaminones. Rsc Adv. 2016, 6,48905-48909. (IF3.289)

 

31.  Shen, J. H.; Xue, L. L.; Lin, X.; Cheng, G.; Cui, X.*, The base-promoted synthesis of multisubstituted benzo b 1,4 oxazepines. Chem. Commun. 2016, 52, 3292-3295. (IF6.567)

30.  Shen, J. H.; Wang, X. D.; Lin, X.; Yang, Z. H.; Cheng, G.; Cui, X.*, One-Pot Regiospecific Synthesis of Quinoxalines via a CH2-Extrusion Reaction. Org. Lett. 2016,18 , 1378-1381. (IF6.732)

29.  Cheng, G.; Li, T.-J.; Yu, J.-Q.*, Practical Pd(II)-Catalyzed C-H Alkylation with Epoxides: One-Step Syntheses of 3,4-Dihydroisocoumarins. J. Am. Chem. Soc. 2015,137, 10950-10953. (IF13.858)

28.  Wang, F.; Shen, J.; Cheng, G.; Cui, X.*, Practical access to 1,3,5-triarylbenzenes from chalcones and DMSO. Rsc Adv. 2015,5, 73180-73183. (IF3.289)

         

27.  Shen, J.; Cai, D.; Kuai, C.; Liu, Y.; Wei, M. e.; Cheng, G.; Cui, X.*, Base-Promoted beta-C(sp(3))-H Functionalization of Enaminones: An Approach to Polysubstituted Pyridines. J. Org. Chem. 2015,80, 6584-6589. (IF4.785)

 

26.  Feng, Y.; Li, Y.; Cheng, G.; Wang, L.; Cui, X.*, Copper-Catalyzed Synthesis of 2-Arylquinazolinones from 2-Arylindoles with Amines or Ammoniums. J. Org. Chem. 2015,80, 7099-7107. (IF4.785)   

  

25.  Cheng, G.*; Weng, Y.; Yang, X.; Cui, X.*, Base-Promoted N-Pyridylation of Heteroarenes Using N-Propargyl Enaminones as Equivalents of Pyridine Scaffolds. Org. Lett. 2015,17, 3790-3793. (IF6.732)                                  

24.  Yang, X.; Cheng, G.*; Shen, J.; Kuai, C.; Cui, X.*, Cleavage of the C-C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones. Org. Chem.Front. 2015,2, 366-368. (IF4.693)    

23.  Wang, X.; Cheng, G.; Shen, J.; Yang, X.; Wei, M.-e.; Feng, Y.; Cui, X.*, A metal-free synthesis of diaryl-1,2-diketones by C-C triple bond cleavage of alkynones. Org. Chem.Front. 2014,1, 1001-1004. (IF4.693)                     

22.  Cheng, G.; Zhang, H.; Cui, X., Copper(I)-catalyzed homo-coupling of terminal alkynes at room temperature under solvent and base free conditions using O2 as an oxidant. RSC Adv. 2014, 4, 1849-1852. (IF3.289)                    

21.  Cheng, G.; Zeng, X.; Cui, X., Benzoquinone-Promoted Aerobic Oxidative Hydroxylation of Arylboronic Acids in Water. Synthesis. 2014, 295-300. (IF2.652)    

                                               

20.  Li, P.; Cheng, G.*; Zhang, H.; Xu, X.; Gao, J.; Cui, X.*, Copper-Catalyzed One-Pot Synthesis of Unsymmetrical Arylurea Derivatives via Tandem Reaction of Diaryliodonium Salts with N-Arylcyanamide.J. Org. Chem. 2014, 79, 8156-8162. (IF4.785)

 

19.  Feng, Y.; Zhang, H.; Cheng, G.*; Cui, X.,Synthesis of Indole Derivatives via Domino Reactions.Chin. J. Org. Chem. 2014, 34, 1499-1508. (IF1.309)

18.  Wang, X.; Cheng, G.; Cui, X., Tandem synthesis of 3-allyl-chromones from alkynones and allylic alcohols under metal-free conditions. Chem. Commun. 2014, 50, 652-654. (IF6.567)  

         

17.  Gao, Y.; Song, Q.; Cheng, G.; Cui, X.,KI-catalyzed arylation of benzothiazoles from the coupling of aryl aldehydes with benzothiazoles in neat water. Org. Biom. Chem. 2014, 12, 1044-1047. (IF3.559)

16.  Cheng, G.; Zeng, X.; Shen, J.; Wang, X.; Cui, X., A metal-free multicomponent cascade reaction for the regiospecific synthesis of 1,5-disubstituted 1,2,3-triazoles. Angew. Chem., Int. Ed. 2013, 52, 13265-13268. (IF11.994)                                                   

15.  Shen, J.; Cheng, G.; Cui, X., "One pot" regiospecific synthesis of polysubstituted pyrroles from benzylamines and ynones under metal free conditions. Chem. Commun. 2013, 49, 10641-10643. (IF6.567)                             

14.  Shao, C.; Zhang, Q.; Cheng, G.; Cheng, C.; Wang, X.; Hu, Y., Copper(I) Acetate-Catalyzed Cycloaddition between Azomethine Imines and Propiolates under Additive-Free Conditions. Eur. J. Org. Chem. 2013, 6443-6448. (IF3.068)

13.  Cheng, G.; Cui, X., Efficient Approach to 4-Sulfonamidoquinolines via Copper(I)-Catalyzed Cascade Reaction of Sulfonyl Azides with Alkynyl Imines. Org. Lett. 2013, 15, 1480-1483. (IF6.732                                                 

12.  Zeng, X.; Cheng, G.; Shen, J.; Cui, X., Palladium-Catalyzed Oxidative Cross Coupling of N-Tosylhydrazones with Indoles: Synthesis of N-Vinylindoles. Org. Lett. 2013, 15, 3022-3025. (IF6.732                                               

11.  Cheng, G.; Wang, X.; Bao, H.; Cheng, C.; Liu, N.; Hu, Y., Total Syntheses of (-)-Hanishin, (-)-Longmide B, and (-)-Longmide B Methyl Ester via a Novel Preparation of N-Substituted Pyrrole-2-Carboxylates. Org. Lett. 2012, 14, 1062-1065. (IF6.732 


        

10.    Shen, J.; Cheng, G.; Cui, X., Domino Reactions Based on Pd-Catalyzed C-H Bond Activation.Prog. Chem.2012, 24, 1324-1336. (IF0.894)

9.    Wang, Y.; Cheng, G.; Cui, X., Easily Modified Directing Groups for the Palladium-Catalyzed C-H Functionalization. Chinese J. Org. Chem. 2012, 32, 2018-2039. (IF1.309)

8.    Cheng, G.; Wang, X.; Zhu, R.; Shao, C.; Xu, J.; Hu, Y., Total Synthesis of (-)-Cocaine and (-)-Ferruginine. J. Org. Chem. 2011, 76, 2694-2700. (IF4.785)

 

7.    Cheng, G.; Wang, X.; Su, D.; Liu, H.; Liu, F.; Hu, Y., Preparation of Enantiopure Substituted Piperidines Containing 2-Alkene or 2-Alkyne Chains: Application to Total Syntheses of Natural Quinolizidine-Alkaloids. J. Org. Chem. 2010, 75, 1911-1916. (IF4.785)

 

6.    Xu, J.; Wang, X.; Shao, C.; Su, D.; Cheng, G.; Hu, Y., Highly Efficient Synthesis of Phenols by Copper-Catalyzed Oxidative Hydroxylation of Arylboronic Acids at Room Temperature in Water. Org. Lett. 2010, 12, 1964-1967. (IF6.732)

 

5.    Shao, C.; Cheng, G.; Su, D.; Xu, J.; Wang, X.; Hu, Y., Copper(I) Acetate: A Structurally Simple but Highly Efficient Dinuclear Catalyst for Copper-Catalyzed Azide-Alkyne Cycloaddition. Adv. Synth. Catal.2010, 352, 1587-1592. 


4.    Liu, H.; Su, D.; Cheng, G.; Xu, J.; Wang, X.; Hu, Y., Enantiopure 2,6-disubstituted piperidines bearing one alkene- or alkyne-containing substituent: preparation and application to total syntheses of indolizidine-alkaloids. Org. Biom. Chem. 2010, 8, 1899-1904. (IF3.559)                                                


3.    Xu, J.; Cheng, G.; Su, D.; Liu, Y.; Wang, X.; Hu, Y., Direct ortho-Arylation of N-Phenacylpyridinium Bromide by Palladium-Catalyzed C-H-Bond Activation. Chem-Eur. J. 2009, 15, 13105-13110. (IF5.771)     


2.    Liu, B.; Su, D.; Cheng, G.; Liu, H.; Wang, X.; Hu, Y., An Efficient Method for the Preparation of Versatile Building Blocks: 1-Substituted 2,2-Dimethoxyethylamine Hydrochlorides. Synthesis 2009, 3227-3232. (IF2.652)                                                

 

1. 戴立言;程国林;王晓钟;陈英奇,2-巯基-5-甲氧基咪唑并[4,5-b]吡啶的合成工艺。化工学报,2007, 3, 656-659.(EI)